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Anti-cancer PF299804 Dacomitinib cas 1110813-31-4

Anti-cancer PF299804 Dacomitinib cas 1110813-31-4
Anti-cancer PF299804 Dacomitinib cas 1110813-31-4
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Product Code : 1110813-31-4
Brand Name : DM
Price And Quantity
  • Minimum Order Quantity
  • 1 Gram
  • Price Range
  • 1.00 - 5.00 USD ($)/Gram
Product Specifications
  • Storage
  • Room Temperature
  • Smell
  • No Smell
  • Molecular Formula
  • C24H25ClFN5O2
  • Taste
  • Odorless
  • Boiling point
  • 665.7±55.0 °C(Predicted)
  • Shelf Life
  • 2 Years
  • Structural Formula
  • C24H25ClFN5O2
  • Molecular Weight
  • 469.9390032 Pound (lb)
  • Medicine Name
  • Dacomitinib (PF299804)
  • Chemical Name
  • (E)-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-Methoxyquizolin-6-yl)-4-(piperidin-1-yl)but-2-eMide
  • CAS No
  • 1110813-31-4
  • Type
  • Pharmaceutical Intermediates
  • Grade
  • Medicine Grade
  • Usage
  • human pharma
  • Purity(%)
  • 99
  • Appearance
  • white powder
  • Physical Form
  • Powder
Product Description

Dacomitinib is a selective and irreversible inhibitor of EGFR. It is a drug candidate for the treatment of non-small cell lung carcinoma. It is current under the Phase III clinical trials. It also shows potential for the treatment of HER-2 amplified breast cancer cells lines that are resistant to trastuzumab and lapatinib. 

Dacomitinib is taken orally once-daily. It is an irreversible inhibitor of HER-1 (EGFR), HER-2 and HER-4 tyrosine kinases. Dacomitinib targets multiple receptors of the HER pathway, whereas currently marketed HER-1 (EGFR) inhibitors for non-small cell lung cancer (NSCLC) target only one receptor in this pathway,developed .

 

Product Name Dacomitinib
Synonyms PF-299804 (Dacomitinib,PF-00299804);PF299804, PF299);Dacomitinib;PF-00299804-03;PF-00299804;DacoMitinib (PF-00299804);DacoMitinib,PF299804;DacoMitinib (PF299804,PF-00299804)
CAS 1110813-31-4
MF C24H25ClFN5O2
MW 469.9390032
EINECS N/A
Product Categories -;Anti-cancer&immunity;Inhibitors
Mol File 1110813-31-4.mol
Trade Information
  • FOB Port
  • shanghai
  • Payment Terms
  • Paypal, Telegraphic Transfer (T/T), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C)
  • Supply Ability
  • 150 Gram Per Month
  • Delivery Time
  • 7 Years
  • Sample Policy
  • If order is confirmed we will reimburse the sample cost
  • Packaging Details
  • Doule PE + aluminium bag
  • Main Export Market(s)
  • Eastern Europe, South America, North America, Central America, Australia, Asia
  • Main Domestic Market
  • All India
  • Certifications
  • ISO9001

SHIJIAZHUANG DINGMIN PHARMACEUTICAL SCIENCES CO., LTD.
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SHIJIAZHUANG DINGMIN PHARMACEUTICAL SCIENCES CO., LTD.
B No.52 Zhaiying South street,Yuhua Dostrict, Shijiazhuang, China, Shijiazhuang - 050000, Hebei, China
Ms. Lily (General Manager)
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