Ivacaftor Powder/ VX-770

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Product Code : 873054-44-5

Brand Name : DM

Price And Quantity

Minimum Order Quantity
1g Gram
Price Range
10.00 - 25.00 USD ($)

Product Description

Specification

Item Name	Ivacaftor
CAS NO	873054-44-5
Apparence	White Powder
Package	Aluminum Bag;Drums;Paper Box Outside
Shipment	FedEx;DHL;UPS;TNT;EMS;Sea;Air.
Payment	Western Union;T/T;Trade Assurance;L/C
Warranty	2 Years

Certification of Analysis

Item	Specification
Specific rotation	+39.5 to +41.5 °
State of solution(transmittance)	Clear 98.0% min.
Chloride[cl]	0.020% max.
Ammonium [NH4]	0.02% max.
Sulfate[SO4]	0.020% max
Iron[Fe]	10ppm max.
Heavy metals [Pb]	10ppm max
Arsenic[As2O3]	1ppm max
Other amino acids	Chromatographically not detectable
Loss on drying	0.20% max.
Residue on ignition[sulfated]	0.10% max.
Assay	99.0% min

Function & Application

Ivacaftor is a new therapeutic agent that actsat the cystic fibrosis transmembrane conductance regulator (CFTR) channel toalter activity. It is approved for use in patients 6 years and older withcystic fibrosis who have at least 1 G551D mutation in the CFTR gene. It isunlike any other current pharmacologic agent for cystic fibrosis in that itspecifically targets the gene defect associated with cystic fibrosis as opposedto treating resulting symptomology. Mucoactive agents, antibiotics, inhaledbeta agonists, and other anti-inflammatory agents are currently the mainstay ofcystic fibrosis treatment but can be associated with several side effects inaddition to cumbersome frequency of administration. Ivacaftor's oral dosingregimen offers a more convenient treatment option.

Trade Information

FOB Port
any port in China
Payment Terms
Cash Against Delivery (CAD), Cash in Advance (CID), Days after Acceptance (DA), Letter of Credit at Sight (Sight L/C), Paypal