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prucalopride succinate/ Cas No 179474-85-2

prucalopride succinate/ Cas No 179474-85-2
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Product Code : 179474-85-2
Brand Name : DM
Price And Quantity
  • Minimum Order Quantity
  • 1g Gram
  • Price Range
  • 10.00 - 50.00 USD ($)
Product Specifications
  • HS Code
  • 29339900
  • Structural Formula
  • C18H26ClN3O3.C4H6O4
  • Smell
  • No Smell
  • 680-639-5
  • Molecular Weight
  • 485.95838
  • Taste
  • Odorless
  • Storage
  • Room Temperature
  • Shelf Life
  • 2 Years
  • Molecular Formula
  • C18H26ClN3O3.C4H6O4
  • Medicine Name
  • Prucalopride succinate
  • Chemical Name
  • Butanedioic acid 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide
  • CAS No
  • 179474-85-2
  • Type
  • Pharmaceutical Intermediates
  • Grade
  • Medicine Grade
  • Usage
  • pharmaceutical Intermediates
  • Purity(%)
  • 99
  • Appearance
  • white powder
  • Physical Form
  • Powder
Product Description

Prucalopride induced contraction in a concentration dependentmanner, with a pEC50 of 7.5. Prucalopride (1, mM) significantly increased therebound contraction after electrical stimulation of the proximal colon ofguinea pigs. Prucalopride induced the relaxation of the mucosal base of theesophagus in rats, whose pEC50 was 7.8, yielding a single phase concentrationresponse curve. Prucalopride (0.1 M) concentration dependently increased theamplitude of non essential base energy contraction and acetylcholine releaseinduced by electric field stimulation in the porcine gastric ring muscle, whichcould be induced and strengthened by IBMX (10 M). Prucalopride (1 M) couldsignificantly increase the electrically induced cholinergic contraction ofporcine descending colon, and the facilitation could be significantly enhancedby Rolipram.

By stimulating the high amplitude cluster contraction of theproximal colon and inhibiting the terminal colonic contractile activity offasted dogs, Prucalopride dependently altered colonic contractile patterns.Prucalopride also caused a dose-dependent decrease in the first giant migrationcontraction (GMC) time; higher doses of prucalopride, the first GMC usuallyoccurred within the first half an hour after treatment.

Trade Information
  • FOB Port
  • any port in China
  • Payment Terms
  • Paypal, Letter of Credit at Sight (Sight L/C), Days after Acceptance (DA), Cash in Advance (CID), Cash Against Delivery (CAD)
  • Supply Ability
  • 100kgs Per Month
  • Delivery Time
  • 1 Week
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • as per request
  • Main Export Market(s)
  • Africa, Western Europe, South America, North America, Central America, Asia
  • Main Domestic Market
  • All India
  • Certifications
  • ISO9001


B No.52 Zhaiying South street,Yuhua Dostrict, Shijiazhuang, China, Shijiazhuang - 050000, Hebei, China
Ms. Lily (General Manager)

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