cas 283173-50-2 Rucaparib APIs

cas 283173-50-2 Rucaparib APIs
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Product Code : 283173-50-2
Brand Name : DM
Price And Quantity
  • Minimum Order Quantity
  • 1g Gram
  • Price Range
  • 10.00 - 50.00 USD ($)
Product Specifications
  • Storage
  • Room Temperature
  • Smell
  • No Smell
  • Shelf Life
  • 2 Years
  • HS Code
  • 29339900
  • Molecular Formula
  • C19H18FN3O
  • EINECS No
  • 814-445-0
  • Structural Formula
  • C19H18FN3O
  • Taste
  • Odorless
  • Medicine Name
  • Rucaparib
  • Chemical Name
  • 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one
  • CAS No
  • 283173-50-2
  • Type
  • Pharmaceutical Intermediates
  • Grade
  • Medicine Grade
  • Usage
  • pharmaceutical Intermediates
  • Purity(%)
  • 99
  • Appearance
  • white powder
  • Physical Form
  • Powder
Product Description

Other name:Rucaparib intermediates,8-fluoro-1345-tetrahydro-2-[4-[(methylamino)methyl]phenyl]

Cas:283173-50-2

Molecular formula:C19H18FN3O

Density:1.281 g/cm3

Color:283173-50-2

Purity:99%

Usage:Rucaparib intermediates

Rucaparib is a PARP inhibitor used as an anti-cancer agent. Rucaparib is a first-in-class pharmaceutical drug targeting the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1). It was discovered as part of a collaboration between scientists working at the Northern Institute of Cancer Research and Medical School of Newcastle University and Agouron Pharmaceuticals in San Diego, California.[2] It is being developed by Clovis Oncology.

In December 2016, the U.S. FDA granted an accelerated approval for use in cases of pretreated advanced ovarian cancer.[3]

In Europe it was designated as an orphan medicinal product on 10 October 2012. On 22 March 2018 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a conditional marketing authorisation, intended for the treatment of relapsed or progressive ovarian cancer.[4]

Trade Information
  • FOB Port
  • any port in China
  • Payment Terms
  • Cash Against Delivery (CAD), Days after Acceptance (DA), Letter of Credit at Sight (Sight L/C), Paypal, Cash in Advance (CID)
  • Supply Ability
  • 100 Gram Per Month
  • Delivery Time
  • 1 Week
  • Sample Policy
  • Within a certain price range free samples are available
  • Packaging Details
  • as per request
  • Main Export Market(s)
  • North America, South America, Western Europe, Africa, Central America, Asia
  • Main Domestic Market
  • All India
  • Certifications
  • ISO9001
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